2024-2025 / PATH0132-1

General principles of clinical diagnosis and of therapeutic

Duration

41h Th, 5h Pr

Number of credits

 Bachelor in medicine4 crédits 

Lecturer

Vincent Bonhomme, Giovanni Briganti, Laurence de Leval, Philippe Delvenne, André Gothot, Marie-Pierre Hayette, Roland Hustinx, Paul Meunier, Régis Radermecker

Coordinator

Philippe Delvenne

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This module is an introduction to the medical approach leading to the most accurate diagnosis through the prescription of paraclinical tests and to the choice, in the therapeutic arsenal, of the most appropriate treatment.

It combines various courses with specific contents:

Pharmacology:
A correct diagnosis is essential before initiating pharmacological therapy or not.

Pathological anatomy:
This course describes the basic principles leading to the screening, diagnosis, prognosis and therapeutic response assessment of the diseases. By determining their etiology, pathology and the anatomical lesions which are  induced, it helps to understand the consequences of aggressions on organ functions and their clinical expressions as diseases.

Clinical biology:
Introduction to the different areas of clinical biology, mainly clinical chemistry, biological hematology, medical microbiology and clinical toxicology.

Radiology:
Practical (technical and clinical) bases of understanding and guidelines for optimal prescription and interpretation of diagnostic imaging.

Nuclear medicine:
Description of the main diagnostic and therapeutic procedures, oncological diseases and non-oncological pathology.
Examples of integration in the diagnostic and therapeutic algorithms.
Basics of dosimetry and radiation protection.

Learning outcomes of the learning unit

The objectives of this module are (1) to demonstrate to the students the contribution of para-clinical tests in the diagnosis of diseases and (2) to provide general and transversal concepts on their therapeutic management.

These general objectives cover specific learning outcomes:

Pathological anatomy:
To determine the place of pathology in the clinical management (screening, diagnosis, prognosis, therapeutic response evaluation, ...).
To understand the causes, responses and morphological consequences of aggressions on various anatomical systems through macroscopic and microscopic aspects of disease.

Clinical Biology:
In each of the areas of Clinical Biology, the methodology of the most commonly prescribed analyzes will be presented, as well as the principles and limits of interpretation. Will be mainly discussed:
Clinical chemistry: plasma and urine; markers of the main functions; an interpretation of clinical chemistry balance.
Biological hematology: exploration of the blood count and hemostasis balance.
Clinical Microbiology: proper prescribing practices and interpretation in microbiology:



  • Knowledge and limits of the different methods and microorganisms means of detection, diagnosis and monitoring of infections.
  • Preanalytical aspects: importance of choosing the types of sampling, analytical approach to volumes, sampling equipment, transport conditions.
  • Prescribing rules under INAMI conditions.
  • Usual time for obtaining results.
  • Examples of direct examination of result interpretation, culture, PCR, antigen detection and susceptibility to infectious serology.
Clinical toxicology: the ory and practice of therapeutic drug monitoring.
 
Radiology:
Practical knowledge of techniques, indications and contra-indications to optimize the prescription strategy.Basics of interpretation.

Nuclear medicine:
To ensure the theoretical training of the future physician to diagnostic and therapeutic techniques of nuclear medicine.

Prerequisite knowledge and skills

Co and pre-requisites are detailed in the general Baccalaureate Medical formation (global course program).

Pathological anatomy:
A good knowledge of histology and general pathology is essential.

Clinical biology:
Multidisciplinary approach of different systems and devices. General microbiology and medical microbiology.

Radiology:
PHYS3018-1 (Maryse Hoebeke): Physical and technical bases (Tray 1).

Nuclear medicine:
Module basic sciences - physics.
PHYS3018-1: Physical basis of medical science, including physical bases of medical imaging - Maryse Hoebeke - [20h REPE]

 

Planned learning activities and teaching methods

This module is multidisciplinary and consists of lectures, supplemented by several sessions of practical activities. Clinical formations are included in another course code and complete the diagnosis learning by a patient-centered approach.

Mode of delivery (face to face, distance learning, hybrid learning)

Blended learning


Additional information:

Face-to-face teaching and/or distance-learning (flipped classrooms)

Course materials and recommended or required readings

Platform(s) used for course materials:
- eCampus
- MyULiège


Further information:

Slides, podcasts and course notes are made available to the students on MyULiege and / or on eCampus web sites.

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )

Work placement(s)

See the educational commitment during MSTG3002-1

Organisational remarks and main changes to the course

Consult the Vade Mecum for students.

Contacts

Coordinator of the module:

Professor Ph. Delvenne

Pathology Department

ICAB, Sart Tilman.

Tel .: 04 /323.11.67

Association of one or more MOOCs

Items online

Slides of Prof. Bonhomme - Lecture given on March 8, 2023
Slides of the course.

Healthy aging, individual aging, functional reserve and frailty
This lecture will be in french.

The topic concerns healthy aging, functional reserve and frailty.

Prescription and interpretation of complementary exams - Prof. Bonhomme - Lecture given on 021924
Slides of the lecture.