Multidisciplinary approach to the genital system

Duration

34h Th

Number of credits

Lecturer

Frédéric Goffin, Philippe Kolh, Aude Lagier, Bernard Lambermont, Pascale Quatresooz, Marc Radermecker

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This module addresses the different anatomical, histological, biochemical, physiological, pathophysiological, and embryological aspects of the genital system.

At the anatomical level, knowledge of the different elements, as well as their interrelationship, is of considerable importance in medical practice. Knowing how to locate the elements, palpate them, recognize them on x-ray images, ... is common practice.

 
At the histological level, the student will learn to know the microscopic aspect of all the organs and the relation between this aspect and the functions of these. He will learn in practical work the criteria allowing him to establish a differential diagnosis and to interpret the aspects of these organs on microscopic sections.  

With regard to biochemistry and physiology, the notion of endocrine network will be defined and the relationship between the genital system and the functioning of the main endocrine glands will be examined. The different mechanisms of hormone release and their modes of action will be explained, as well as the elements necessary to understand the basic explorations of the different endocrine functions. Some physiopathological aspects will be presented as benchmarks. The examination of the synergistic, antagonistic and permissive effects of sex hormones and their regulation will be reviewed. Notions of reproductive biology will also be discussed. Fertilization and the physiology of pregnant women will also be discussed. Normal obstetric mechanics as well as breastfeeding are also part of this module.


The course of biochemistry and physiology of the male genital system has the following sections:

• sexual differentiation
• secretion of sex hormones
• puberty and growth
• associated pathologies

• Hypothalamo-pituitary axis function
• Ovarian cycle
• Menstrual cycle
• Fecondation and embryonic implantation
• Adapatations and physiological modifications associated to pregnancy
• Normal delivery: foetus and placenta
• The placenta, 
•  

Learning outcomes of the learning unit

Overall, by the end of this course, you should know, understand, and describe:

• The functioning of the hypothalamic-pituitary axis
• The role of the hypothalamus and pituitary gland in triggering ovulation
• The hypothalamic-pituitary secretions related to the ovarian and menstrual cycles
• The different phases of the ovarian cycle
• Follicular growth up to ovulation
• The endocrine and exocrine functions of the ovary
• The stages of ovarian steroid hormone synthesis
• The ovarian steroid feedback mechanisms on the hypothalamic-pituitary axis
• The bi-cellular theory of ovarian steroid secretion
• The mechanisms of ovulation
• The peripheral effects of progesterone and estrogens
• The different successive phases of the endometrial cycle, including the implantation window
• The onset of menstruation
• Embryo implantation
• Human placentation
• The role of human chorionic gonadotropin (hCG)
• Abnormalities of the female and male reproductive systems
• Contraceptive mechanisms, both hormonal and non-hormonal
• Ovarian stimulation methods
• Various causes of female and male infertility
• Assisted reproductive technologies
• The different phases of a normal pregnancy
• Maternal physiological changes associated with pregnancy
• The process of a normal delivery
• The main ethical aspects related to human reproductive biology

Prerequisite knowledge and skills

• Anatomy of the hypothalamo-pituitary system and of the female genital tract
• Histology of the female genital tract
• Embryology of the female genital tract
• Co-requisite: biochemistry and physiology of the endocrine system

Planned learning activities and teaching methods

This Module is multidisciplinar (based on different theoretical courses in different disciplines).
Practical works (MEDE0124 and MEDE0125) and Problem-based seminars (APPR0141) complete the practical and clinical aspects.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Further information:

Hybrid course (theoretical aspects in classical classrooms ; some practical aspects are developped within e-learning and small groups sessions).

Ex-cathedra lectures: 6x2h
* The hypothalamic-pituitary axis
* The ovarian cycle, its endocrine and ovulatory functions
* The endometrial cycle, the implantation window, menstruation
* Fertilization, embryo implantation
* Placentation
* Pregnancy and childbirth
* Principles of fertility control and preservation
* Introduction to ethical aspects related to human reproductive biology

 

Course materials and recommended or required readings

Platform(s) used for course materials:
- eCampus


Further information:

Slides and comments are available on e-campus on line course ; books can be obtained at the Ulg Press Shop  (complementary, not compulsory).

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )

Out-of-session test(s)


Further information:

Written exam :QROC and QCM in june and september

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Professor Frédéric Goffin
fgoffin@uliege.be


Secretary:
Christelle Leclercq
christelle.leclercq@chrcitadelle.be



Pr Philippe KOLH

Human biochemistry and physiology

philippe.kolh@uliege.be

04/3665196

04/3668445 (secrétariat)


Professor P.BONNET - Anatomie humaine, Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23 (Tél.: 04/366.51.57 ; e-mail: P.Bonnet@ulg.ac.be (pour problèmes non relatifs au cours; sinon utiliser le forum "on-line")

Chef de Travaux

Dr Valérie Defaweux Anatomie humaine, Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23

Tél.: +32 4 3665174 +32 4 3662858

e-mail: Valerie.Defaweux@ulg.ac.be

Secretary :

Jessica Thys

Tour de Pathologie 2 - Bât. B36 +1

4000 LIEGE

Tél: 04/366.51.91

Fax: 04/366.59.53

Jessica.Thys@ulg.ac.be

MERCI DE COMMUNIQUER VIA LE COURS EN LIGNE ET d'EVITER DE CONTACTER LE SERVICE CLINIQUE

Anatomie Prosecteurs: Madame M. Wouters, Messieurs G.Dessers, A. Botte

Tour de Pathologie 3, niveau -1, CHU Sart Tilman, Bât. B23 (Tél.: 04/366.51.52-3

Association of one or more MOOCs

Items online