2024-2025 / SBIM2030-1

Advances I in Clinical Biology

Duration

15h Th, 15h Pr

Number of credits

 Master in biomedicine, research focus3 crédits 
 Master in biomedicine, professional focus in biomedical data management3 crédits 
 Master in biomedicine, professional focus in quality assurance3 crédits 
 Master in biomedicine, professional focus in clinical research management3 crédits 

Lecturer

Pablo Beckers, Sébastien Bontems, Khalid El Moussaoui, Cécile Meex, Rosalie Sacheli

Coordinator

Marie-Pierre Hayette

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

COORDINATOR:Hayette Marie-Pierre

Instructors: Rosalie Sacheli, Sébastien Bontems, Cécile Meex, Pablo Beckers, Khalid El Moussaoui.


Clinical Microbiology

Instructors: Sébastien Bontems, Cécile Meex, Rosalie Sacheli, Khalid El Moussaoui, Pablo Beckers.

Content: Theoretical Part

The theoretical course will be delivered in:

- 2 hours by Cécile Meex:Introduction to the flow of a microbiological sample within the dispatching, bacteriology, and serology sectors, along with a brief overview of the various analyses offered by these sectors.

- 2 hours by Sébastien Bontems: Introduction to the flow of a sample and the different analyses in the molecular biology sector, as well as general principles of quality assurance in microbiology.

- 2 hours by Rosalie Sacheli:Presentation of the role of national reference centers within the microbiology laboratory and their various missions at the national level (data transfer to Sciensano, drafting annual epidemiological reports, etc.).

- 2 hours by Pablo Beckers: Serology

- 2 hours by Khalid El Moussaoui: Reference laboratory for HIV/AIDS


Practical Part:

Observation of a sector in the clinical microbiology laboratory of CHU Liège in groups (bacteriology, molecular biology, national reference centers, serology, etc.).

- Identification of workflows including the identification of premises, detailing pre-analytical, analytical, and post-analytical workflows (description of procedures, types of samples, automates used, daily sample volumes, time taken, etc.).

- Identification of advantages and disadvantages of observed methods.

- Verification of compliance with safety and hygiene measures in the laboratory (wearing gloves, lab coats, etc.).

Ultimately, students will be able to conduct a mini-audit of the sector based on key points from the ISO 15189 standard.


Learning Outcomes:

By the end of the course, students will be able to:

1. Differentiate between various sectors in microbiology and their respective missions.
2. Understand and visualize the complete flow of a sample within these sectors.
3. Summarize the principles, advantages, disadvantages, and positioning of analytical techniques used in the different sectors of microbiology (microscopic, immunological, culture, molecular biology) and outline the main stages in the evolution of techniques in microbiology, including the introduction of automation and pursued improvement objectives.
4. Explain and justify the analytical characteristics required for screening, diagnostic, and confirmation tests.
5. Argue the importance of obtaining rapid results.
6. Understand the application of ISO 15189 standards within the microbiology sector.
7. Consider an approach to compiling and presenting epidemiological data and new technical knowledge in a complex and evolving process associated with a specific infectious agent, particularly in the context of the activities of reference centers, and understand how to compile and present this data for public information.


Teaching Mode:

The instruction primarily consists of in-person lectures with encouragement for discussion during class. The lecture slides are available online via "my ULg." For practical work, students will spend two half-days in the clinical microbiology laboratory at CHU. The examination will take the form of a group oral presentation (3-4 students) based on the practical exercise conducted in the laboratory for the sector chosen by the students.

Learning outcomes of the learning unit

Prerequisite knowledge and skills

Planned learning activities and teaching methods

Mode of delivery (face to face, distance learning, hybrid learning)

Course materials and recommended or required readings

Written work / report

Other : oral presentation of the report

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Stéphanie Wauquier 04/323.22.90 (Stephanie.Wauquier@chuliege.be)

Association of one or more MOOCs

Items online

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