Duration
20h Th, 15h Pr
Number of credits
| Master in bio-informatics and modelling, research focus | 3 crédits |
Lecturer
Coordinator
Language(s) of instruction
English language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Objectives and program:
1) the tools needed for visualization and analysis of biological macromolecules,
2) an overview of protein modeling methods: homology modeling, ab initio modeling, proteins and ligands, docking methods, etc ...
The course will cover
- a reminder of the protein structure (if necessary ...),
- an introduction to the Protein Data Bank and description of a PDB file,
- an introduction to the Pymol visualization program and TPs on its use,
- the use of 3D structural analysis software (deepview software, PDBePISA)
- modeling by homology - Introduction to the Yasara and TP program on its use
- Protein-Ligand interactions - Introduction to AUTODOCK software
Learning outcomes of the learning unit
Prerequisite knowledge and skills
Planned learning activities and teaching methods
The use of the different software discussed requires the use of a laptop.
Mode of delivery (face to face, distance learning, hybrid learning)
Face to face
Course materials and recommended or required readings
Power points Softwares access
The examination will consist in the realization of a work and report based on the study of a practical case whose title will be given beforehand.
Work placement(s)
Organisational remarks and main changes to the course
20 lessons of 2 hours.
Contacts
Dr Frédéric Kerff- Tél. 04/366.36.20 - E-mail : fkerff@uliege.be