Duration
57h Th, 18h Pr, 9h AUTR
Number of credits
| Master in bioengineering : chemistry and bio-industries (120 ECTS) | 8 crédits |
Lecturer
Frank Delvigne, Patrick Fickers, Philippe Jacques, Marc Ongena, Jean-Claude Twizere
Coordinator
Language(s) of instruction
English language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
This course focus on theoretical and practical aspects on technologies related to the production of compounds of biotechnological interest (biomass, proteins, metabolites) for agro-food, chemical and biopharmaceutical industries. The course details the different technologies of bioreactor culture, molecular techniques leading to the development of "cell factory" as well as cell-environment interactions.
Learning outcomes of the learning unit
At the end of this multidisciplinary module, students will be able to integrate the different aspects of the development, implementation, optimization and control of a process of production of a compound of interest in bioreactor. The course also includes dimensioning part (calculation of oxygen transfer capacity, dynamics of microbial growth and production of metabolites, ...) and on the construction of dynamic models of bioprocesses (resolution of first-order differential equations under MatLab).
Prerequisite knowledge and skills
BIOL2010-1 : Biologie cellulaire
BIOL2013-2 : Microbiologie générale - Patrim 1
BIOL2013-3 : Microbiologie générale - Partim 2
BIOL2015-3 : Biologie moléculaire
BIAA0003-1 : Génie industriel alimentaire et ingénierie agro-alimentaire - 1ère partie
CHIM9241-1 : techniques de séparation et de concentration
MATH2016-1 : mathématique générale et modélisation des systèmes dynamiques
Planned learning activities and teaching methods
- Bioreactor engineering (F. Delvigne, 12 h Th)
- Metabolic engineering (P. Fickers, P. Jacques, 12 h Th)
- Microbial interaction (M. Ongena, 12 h Th)
- Animal cell culture (JC Twizere , 12 h Th)
- Exercices (F. Delvigne, P. Fickers, P. Jacques, 12 h, )
- Lab (P. Fickers, P. Jacques, M. Ongena, F. Delvigne, 12 h)
- Numerical simulation (F. Delvigne, 12 h, exercices)
Beside ex-cathedra courses, this module includes practical lab work, exercises (simulation on MatLab), seminars (industrials, academics or research centers) and company visits Active. In this course, a pedagogical approach "learning by doing" will also be favored..
Mode of delivery (face to face, distance learning, hybrid learning)
Lectures
Lab training
Exercices (numerical simulation using MatLab),
Seminars
Company visit
In this course, a pedagogical approach "learning by doing" will also be favored.
Recommended or required readings
Report and oral presentation
Oral and writen exam
Work placement(s)
Organisational remarks and main changes to the course
Contacts
Prof. Patrick Fickers
Microbial Processes and Interactions (MiPI)
Ph: 081 622 311 (direct), 081 622 305 (secretariat)
pfickers@ulg.ac.be
Association of one or more MOOCs
Items online
Fickers_2022_Centrifugation_Filtration
Lecture on centrifugation and filtration
Fickers_2022_Metabolic engineering
Lecture on Metabolic Engineering
Interactome networks to understand genotype-phenotype relationships
The slides contain key slides to explain genotype - phenotype relationships, based on the understanding genotype-phenotype relationships. We will focus on protein-protein interactions technologies and give pratical examples.