Duration
34h Th, 10h APP
Number of credits
| Master in biomedicine, research focus | 5 crédits | |||
| Advanced Master in Nanotechnologies | 5 crédits |
Lecturer
Pascal De Tullio, Keith Durkin, Marianne Fillet, Gabriel Mazzucchelli
Language(s) of instruction
English language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
This course provides an in-depth introduction to cutting-edge omics approaches in biomedical, (bio)pharmaceutical research and clinical applications.
Students will explore the fundamentals and the applications of omics, including genomics, transcriptomics, proteomics, metabolomics, and lipidomics, and understand their crucial role as holistic tools in human health and in the pharmaceutical area. Emphasis will be placed on their applications at both the preclinical and clinical levels.
The different courses will be organized according to the following table of contents:
Basic anatomy of the genome, variation in the genome, the morbid genome, assaying the genome, assaying the transcriptome and epigenome, Impact of proteomics in clinical and (bio)pharmaceutical fields, proteomics experimental design for in drug discovery and clinical biomarker discovery, metabolomics and fluxomics généralities, metabolomics in drug discovery, metabolomics in personalized medicine, lipidomics and multiomics.
Learning outcomes of the learning unit
At the end of this course, students will be able to understand the importance of omics sciences in research and clinical applications, as well as to know the analytical principles and practical aspects of these techniques.
Prerequisite knowledge and skills
This course is dedicated to medical, biomedical and pharmaceutical students with a background in cells and human physiology.
Planned learning activities and teaching methods
This course is mainly given ex cathedra, with additional references to renowned book chapters and reviews.
Journal-club sessions could be organized at the end of the different omics presentation and implicate the active participation of the students.
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Further information:
Face-to-face: this course is mainly given ex cathedra.
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
Further information:
The slides projected during the course will be distributed to students (eCampus).
Exam(s) in session
Any session
- In-person
written exam ( open-ended questions )
Further information:
written exam (3h)
Work placement(s)
Organisational remarks and main changes to the course
Contacts
The course will be taught by Mr. Fillet, Ms. Durkin, Mrs. de Tullio, and Ms. Mazzucchelli.
Contact:
Dr. Pascal de Tullio, FNRS Research Director
Laboratoire de Chimie Pharmaceutique
Avenue Hippocrate 15, B-4000 Liège
CHU Tour 4, niveau +5 (B36)
Tél. 04/366 43 73
E-mail : P.detullio@uliege.be