Duration
26h Th, 4h AUTR
Number of credits
Lecturer
Christine Gilles, Nathalie Jacobs, Agnès Noël, Marie-Julie Nokin, Nor Eddine Sounni
Language(s) of instruction
English language
Organisation and examination
Teaching in the first semester, review in January
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Different topics will be presented
Hallmarks of Cancer:
Description and presentation of the hallmarks of cancer (A. Noel)
Introduction to preclinical models:
Generation of KO, KI and PDX mouse models (A. Noel)
Introduction to pre-clinical models of cancer (N.E. Sounni)
Genomic instability and epigenetics in cancer:
Introduction to genomic instability in tumors (M.J. Nokin)
Introduction to cancer epigenetics (M.J. Nokin)
Tumor Microenvironment #1:
Fibroblasts in cancer (A. Noel)
Angiogenesis (N.E. Sounni)
Tumor heterogeneity, plasticity and EMT
Tumor plasticity, epithelial to mesenchymal transition (C. Gilles)
Tumor Microenvironment #2:
Cancer immunity (N. Jacobs)
Cancer immunotherapy (N. Jacobs)
Cancer Metabolism:
Introduction to metabolic pathways in cancer, (N.E Sounni)
Hypoxia, metabolism, and epigenetic regulation (N.E Sounni)
Learning outcomes of the learning unit
To introduce the different common characteristics of tumor cells and the importance of the micro-environment.
To obtain enough basic knowledges to fully understand and be critic towards scientific publications, experimental essays and clinical trials.
At the end of the course, the student should be able to interpret a figure from a literature's review article related to the thematic covered in the course
Prerequisite knowledge and skills
Molecular biology, mechanism of cell signaling and signaling cascades
Planned learning activities and teaching methods
Different sets of lectures will be given by the Professors A. Noël, M.J. Nokin, C. Gilles, N. Jacobs et N.E. Sounni, in function of their expertise.
The last two lessons could be devoted to a revision or questions/answers and to learn how to describe scientific figures.
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Further information:
Face to face
Course materials and recommended or required readings
Platform(s) used for course materials:
- eCampus
- MyULiège
- Microsoft Teams
Further information:
The slideshow will be communicated to students. In the event of a possible problem accessing the slideshow, students are invited to contact the teacher or the coordinator (N.E. Sounni) a maximum one week before the exam.
Slideshow will be given to the students
Exam(s) in session
Any session
- In-person
written exam ( open-ended questions )
Further information:
Exam(s) in session
Any session
- In-person
written exam (open-ended questions)
Additional information:
Written exam (with the possibility to answer in English or French) to assess both knowledge and comprehension. This exam could contain questions with short or long answers
For the present academic year (2024-2025), the repeaters will only be questioned on the 2023/2024 course program SBIM2002 A-a.
Work placement(s)
None
Organisational remarks and main changes to the course
The lectures will be given in English. Exceptionally, some further explanations could be given in French if required.
Contacts
Agnès Noël
email : agnes.noel@uliege.be
Phone: 04/366 25 69
Marie-Julie Nokin
email : mjnokin@uliege.be
Christine Gilles
email: cgilles@uliege.be
Nathalie Jacobs. couriel : n.jacobs@uliege.be
Nor Edinne Sounni
email: nesounni@uliege.be
Phone: 04/366 25 70