2024-2025 / SBIM0493-2

Elements of microbiology and general immunology

Duration

12h Th

Number of credits

 Bachelor in physiotherapy and rehabilitation1 crédit 
 Bachelor in motor sciences1 crédit 

Lecturer

Marie-Pierre Hayette, Nathalie Jacobs

Language(s) of instruction

French language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This course comprises 2 complementary parts: elements of immunology and elements of microbiology.

Immunology contents (N.Jacobs)

The goal of the course is to understand the mechanisms that allow us to defend ourselves against pathogens intrinsically or through vaccination. The negative effects of an uncontrolled immune response will also be discussed.
 


Microbiology contents (MP. Hayette - K. El Moussaoui)



This course introduces students to the invisible world of microbes and their essential roles in our daily lives: most microbes are beneficial and protect our biosphere, while a minority are responsible for disease.  Microorganisms are ubiquitous and live in highly varied and complex ecosystems. Their role in different ecosystems and that of man, who influences the evolution of microorganisms responsible for emerging diseases by acting on the environment, are highlighted.

 

Covered topics :

 

  • Introduction to complexity and evolution in the field of microbiology.
  • Description of the specific characteristics of microorganisms, helping to understand the development of infectious diseases and the means available to control them.
  • Brief presentation of the 4 main groups of microbes: viruses, bacteria, fungi and parasites. Bacteria represent the oldest form of life, at the origin of the evolution of the forms of life we know.
  • Description of the fundamental principles of microbial life, the characteristics of microorganisms, and their interactions with the environment and other living organisms, in particular with man.
  • Description of the complex symbiotic associations between microbes and man: from simple transient colonization to the establishment of a relationship sometimes leading to the declaration of a disease.
  • Description of the main microbial virulence factors and human defenses.
  • Differentiation between pathogenic and opportunistic microorganisms.
  • Principles of different approaches to controlling and preventing infectious diseases: improved hygiene, access to drinking water, use of antimicrobial agents, immunoprophylaxis, sterilization, use of antiseptics and disinfectants.
  • Presentation of recommendations for preventing the transmission of certain pathogens associated with sporting activities.
  • Presentation of infectious risks associated with the microbiological quality of bathing water and means of control.
  • Practical exercises introduce the concepts of biosafety, essential hygiene rules such as hand washing, and basic microbiological techniques.
 

Learning outcomes of the learning unit

Immunology

To know and be able to explain general immunology concepts and vaccination

Microbiology

At the end of this course, students will be able to:

  • identify the main issues surrounding microorganisms on our planet (e.g. environment, infectious pathology)
  • describe the global importance of mortality and the evolution of infectious diseases
  • present some key milestones in the history of microbiology
  • describe the different types of microorganisms and their characteristics
  • summarize the growth characteristics of bacteria and the importance of biofilms
  • describe the genetic material of bacteria, the main principles of its modification and new acquisitions
  • describe the main beneficial aspects of microbes
  • understand and explain the host-microorganism relationships that can lead to disease
  • list and briefly describe the main pathogenic factors
  • explain the different modes of transmission of infectious agents
  • understand and summarize available means of defense and prevention against aggression by microorganisms. Food chain safety / drinking water / vaccination / sterilization-disinfection / antibiotics
  • briefly describe the modes of action of antibiotics and resistance mechanisms
  • describe the methods and means of detection and identification of microorganisms used in laboratories.
  • read and interpret a bathing water microbiological control report
  • Understand the need to implement strategies for maintaining shared sports equipment, and to enforce basic hygiene rules to prevent the transmission of certain pathogens.

Prerequisite knowledge and skills

Prerequisite or corequisite units are presented within each program.

Planned learning activities and teaching methods

Immunology

The course is divided in several face-to-face lectures.

On eCampus portal supplementary information on immunology is available

On student demand a revision lesson (questions-answers) could be organised
 
A quiz will be organised at the end of each face-to-face course to earn a bonus for the exam. This bonus will be valid for one session only.


Microbiology



This course is mainly based on lectures and podcasts.  It is structured in several chapters to ensure a progressive and logical understanding of the content.

Students are invited to ask questions after class or by email, mentioning their section.



 

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Further information:

Face-to-face course


Additional information:

Combining face to face and distance learning activities

Complementary explanations:

 
Face to face ex-cathedra courses.  To meet microbiology prerequisites, courses begin with "Elements of Immunology", necessary for understanding host-parasite relationships developed in the "Elements of Microbiology" section.

Participation of 3 persons for teaching:

  • N. Jacobs
  • MP. Hayette
  • K. El Moussaoui

The slideshows of the theoretical microbiology courses and the practical work manual are online and accessible via "my ULg".

Course materials and recommended or required readings

Platform(s) used for course materials:
- eCampus


Further information:

Immunology:

Slide presentation is available on "eCampus" portal after the lecture.

Microbiology:

Slideshows of theoretical lectures, published online and accessible to students in the sections and year concerned by the course, are mandatory.

 

The following books may be useful references for students: providing a better understanding, developing a topic of interest:

  • MIMS' MEDICAL MICROBIOLOGY, Richard Goering et al, 5th Ed.,2012, Elsevier 
  • INTRODUCION A LA MICROBIOLOGIE, Tortora G.J. et al, 2nd Ed., 2012, ERPI, Editions du Renouveau Pédagogique Inc. 
  • BROCK BIOLOGY OF MICROORGANISMS, MT Madigan et al, 14th Ed, 2014,Pearson 
  • THE MICROBIAL CHALLENGE, Krasner R., 2002, Ed. ASM PRESS 
  • MICROBIOLOGIE, Prescott, Willey JM et al, Traduction de la 8ème Ed,2013, Ed.De Boeck Université
Recommanded Website:

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )


Further information:

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire )

Other : ON LINE EXAMINATION FOR PRACTICAL ACTIVITIES


Additional information:

Immunology

  Writing exam

Microbiology

Written examination in January and September sessions, with multiple-choice questions (MCQs).

To ensure a good understanding of the subjects taught, elements of general immunology (N. Jacobs) precede elements of microbiology (MP. Hayette).

Questions relating to the course (immunology section) should be sent via the "eCampus" portal forum.





 

Work placement(s)

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Organisational remarks and main changes to the course

Questions related to the course (immunology partim) must be posted on the forum of "eCampus" portal.

Contacts

MICROBIOLOGY

Clinical microbiology Department
University Hospital of Liège,
B-23 Sart Tilman,
4000 LIEGE
Belgium

Secretary

For any contact or to fix an appointment, please contact the secretary MRS Wauquier

  • Phone : 00.32.4.323.22.90
  • email : stephanie.wauquier@chuliege.be
Professor

Marie-Pierre Hayette; Khalid El Moussaoui

Training

  • stephanie.wauquier@chuliege.be

IMMUNOLOGY

Professor

Nathalie Jacobs

  • n.jacobs@ulg.ac.be
Cellular and Molecular Immunology-Virology
CHU de Liège, B34 +5

Association of one or more MOOCs