Duration
26h Th, 26h Pr
Number of credits
| Master MSc. in Biomedical Engineering, professional focus | 5 crédits |
Lecturer
Language(s) of instruction
English language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The course will give an introduction to systems and synthetic biology.
The part "introduction to systems biology" covers the emerging properties of dynamical systems, such as robustness, performance, complexity and optimality.
The topics of the theoretical parts on synthetic biology are:
- historical overview of synthetic biology
- tools and approaches in synthetic biology
- DNA sequencing and building of "elementary bricks"
- mathematical modelling
- measurements (microscopy, flow cytometry)
- design of metabolic pathways
- design of regulatory systems
- security, social and ethical aspects
Learning outcomes of the learning unit
At the end of this course, the student will master basic concepts of systems and synthetic biology. He or she will be able to build virtually as well as in E. coli simple synthetic systems.
This course is taught in English, with support material available in English.
This course contributes to the learning outcomes II.1, II.2, III.1, III.3, IV.1, V.2, VI.2, VII.5, VII.6 of the MSc in biomedical engineering.
Prerequisite knowledge and skills
none
Planned learning activities and teaching methods
The course is based on ex-cathedra lectures, and a laboratory project requiring the use of a computer for simulating biochemical reaction systems (Matlab or a software dedicated to simulating biological systems) as well as biological / biochemical manipulations.
This course is taught in English. Students may ask questions in French or English.
Mode of delivery (face to face, distance learning, hybrid learning)
face-to-face
Course materials and recommended or required readings
The systems biology part is based on the book: Uri Alon « An Introduction to Systems Biology: Design Principles of Biological Circuits », Chapman & Hall/CRC Mathematical & Computational Biology, 1996.
Exam(s) in session
Any session
- In-person
oral exam
Additional information:
Detailed individual report (publication style) on the project (25%); oral examen (75%).
Participation in the project is a prerequisite for the final oral exam.
Work placement(s)
Organisational remarks and main changes to the course
The course is organised in the second quadrimestre, at dates to be arranged.
Contacts
Frank DELVIGNE
Gembloux Agro-Bio Tech
Microcial Processes and Interactions
Avenue de la Faculté 2B
5030 Gembloux
Tel 081 622309
F.Delvigne@uliege.be