2024-2025 / BIOC0430-1

Interactions materials - living systems

Duration

25h Th

Number of credits

 Master MSc. in Biomedical Engineering, professional focus3 crédits 
 Master MSc. in Chemical and Materials Science Engineering, professional focus in Chemical Engineering3 crédits 

Lecturer

Dorien Van hede

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

The Interactions Materials-Living Systems course is made up of the following parts:

  • Importance of biomaterials in medicine
  • History and evolution of biomaterials
  • Properties of matter and the main types of biomaterials
  • Methods for characterizing the surface of biomaterials
  • Organization of tissues, homeostasis, and responses to external aggression
  • Biological responses to biomaterials
  • The different methods of evaluating biomaterials and principles of biocompatibility
  • The degradation of biomaterials in the biological environment
  • Examples of medical applications (intraocular lenses, stents, pacemaker, orthopedics, etc.): state of the art, specifications, innovations, in vitro/in vivo evaluation of biocompatibility and performance
Students may also be asked to prepare certain course materials in the form of Powerpoint presentations (journal club) in small groups of 2-3 people. These may be subject to evaluation.

Learning outcomes of the learning unit

At the end of the course, the student will be able to:

  • Know the general properties of biomaterials and understand their impact
  • Cite the methods for characterizing biomaterials and explain their interest(s)
  • Explain the organization of cells and tissues and how the body reacts to injuries
  • Explain the different biological responses that the body puts in place in the presence of a biomaterial
  • Explain the hemocompatibility issues of biomaterials
  • Cite and explain the different tests that exist to assess the risks linked to the use of biomaterials
  • Explain the different modes of biodegradation of materials depending on their nature
  • For each application covered during the course, know the general principle of the biomaterial, the requirements (specifications), the in vitro/in vivo evaluation methods, and current advances.

Prerequisite knowledge and skills

Basic knowledge of chemistry, biochemistry, physics, biology.

Planned learning activities and teaching methods

Theoretical lessons alternated with questions/answers.

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course

Course materials and recommended or required readings

The theoretical course is inspired by the following books:

Biomaterials Science: An Introduction to Materials in Medicine

Foundations of Biomaterials Engineering

 

The course slides will be made available on the MyULiège portal

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )


Further information:

From 10 students, the exam will be written in the form of MCQs, True or False, and/or open questions. For less than 10 students, the exam will be oral, precede by a period of written preparation of the questions.


The evaluation will include the exam score and possibly that of an oral presentation, in this case, the weighting will be as follows:

Written exam: 60%

Oral presentation: 20%

Projet: 20%

Work placement(s)

  /

Organisational remarks and main changes to the course

Course accompanied by questions/answers to promote interactivity.

Contacts

Dorien Van hede, dental-Biomaterials Research Unit, Avenue de l'hôpital 1, 4000 Liège, Site du CHU Route 669

Email : dorien.vanhede@uliege.be

Modalité de rencontre : sur rdv par email

Association of one or more MOOCs