2023-2024 / PHAR0370-1

Pharmacokinetics

Duration

15h Th, 5h QA Sess.

Number of credits

 Bachelor in pharmacy2 crédits 

Lecturer

Corinne Charlier, Raphaël Denooz, Géraldine Piel

Coordinator

Géraldine Piel

Language(s) of instruction

French language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

A. Tools and concepts of biopharmaceuticals and pharmacokinetics (Partim Prof G. Piel)

1. Introduction
2. Absorption
3. Distribution
4. Elimination
5. Plasma profile changes depending on the route of administration: pharmacokinetic calculations ...
6. Nonlinear pharmacokinetics
7. Notions of bioequivalence



B. Pharmacokinetics and concepts of therapeutic drug monitoring (Partim Prof R. Denooz)


I. Pharmacokinetic (Absorption, Distribution, Metabolisation, Elimination)

II. TDM

1. The goals of TDM
2. Which drugs can be monitored?
3. Which patients is it necessary to monitor ?
4. Interpretation of the results and drug doses adaptation

Learning outcomes of the learning unit

The objective of this course is the acquisition of the basic notions of pharmacokinetics necessary for the good use of drugs. The purpose to be reached is the prescription of every medicine to the posology which insures the best efficiency with minimum unwanted effects. The course is illustrated by several examples aiming at a good understanding of the pharmacokinetic section of the scientific leaflet of specialities as well as by the realization of practical exercises.

Prerequisite knowledge and skills

Planned learning activities and teaching methods

For teaching methods, see section below
Learning activities are proposed in the form of exercises

Mode of delivery (face to face, distance learning, hybrid learning)

Face-to-face course


Additional information:

The course will be given face-to-face 

Recommended or required readings

Power point presentations will be available

Exam(s) in session

Any session

- In-person

written exam ( multiple-choice questionnaire, open-ended questions )


Additional information:

The course grade is calculated as follows: Arithmetic mean of the marks obtained for the courses allocated to each teacher.

Please note that the principle of the absorbing mark is applied: if, within the course, one of the two marks is <7/20, this mark is then carried forward as the course average.

Work placement(s)

Organisational remarks and main changes to the course

      

Contacts

Prof. Géraldine PIEL, Laboratory of Pharmaceutical Technology and Biopharmacy Tél : 04/3664308 geraldine.piel@uliege.be
Prof. Raphaël DENOOZ Clinical and Forensic Toxicological laboratory CHU B35 Sart-Tilman, B4000 Liège Tél.04/3667683 or 04/3668816 Fax 04/3668889 e-mail : Raphael.denooz@chuliege.be

Association of one or more MOOCs