Duration
Cardiovascular system : 10h Th
Respiratory system : 10h Th
Nervous system : 20h Th
Nervous system - specific concepts : 2h Pr.
Number of credits
| Bachelor in biomedicine | 5 crédits |
Lecturer
Cardiovascular system : Philippe Kolh
Respiratory system : Didier Cataldo
Nervous system : Gaëtan Garraux
Nervous system - specific concepts : Gilles Vandewalle
Coordinator
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system.
1. Elements of cardio-vascular physiology
2. Cardiac pump
3. Vascular System
4. Cardio-vascular homeostasis : cardiac output and arterial pressure
5. Principles of cardio-vascular physiopathology
6. Arterial hypertension
7. Coronary insufficiency
8. Cardiac failure
II. Respiratory system
1. Introduction to respiratory system
2. Ventilation
3. Diffusion
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...).
III. Digestive system
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption
11. Liver
12. Colon
IV. Nephro-urinary system
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology
6. Urinary tract
V. Endocrine system and metabolism
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
Energetic metabolism
Insulin and diabetes
Glucagon
Epinephrine
Glucocorticoids
Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie
Cardiovascular system
The subject of this module relates to Normal and Pathological Human Biochemistry and Physiology, partim cardiovascular system, broken down in the following chapters:
The heart pump (Chapters I to V):
- Functional architecture (Chapter I)
- Heart chambers
- Valvular apparatus
- The automaticity of the pump (Chapter II)
- The action potential
- Neuro-vegetative modulation
- The cardiac cycle (Chapter III)
- The driving unit
- The pressure-volume loop
- Ventricular performance (Chapter IV)
- The concept of preload
- The concept of afterload
- The concept of contractility
- Myocardial energetics (Chapter V)
The vascular system (Chapter VI):
- The laws of blood flow (Chapter VI)
- Bernoulli's law
- Darcy's law
- Hagen-Poiseuille's law
- Functional architecture (Chapter VI)
- Vascular resistance
- Arterial elasticity
- The blood pressure wave (Chapter VI)
- Vasomotricity (Chapter VI)
- Mechanical self-regulation
- Metabolic self-regulation
- The endothelial function
Cardiovascular control (Chapter VII)
- The relationships of cardiac output
- Control of blood pressure
- The barosensitive reflex
- Hormonal regulation
Elements of cardiovascular physiopathology (Chapters VIII and X)
- Pressure overload (Chapter VIII)
- Volume overload (Chapter VIII)
- Breach of contractility (Chapter VIII)
- The vicious circle of heart failure (Chapter X)
- Circulatory insufficiencies (Chapter X)
- Syncopes
- Shocks
Respiratory system
The course aims at allowing students to be able to understand human biochemistry and physiology
The different systems will be part of the course:
I. Cardio-vascular system.
1. Elements of cardio-vascular physiology
2. Cardiac pump
3. Vascular System
4. Cardio-vascular homeostasis : cardiac output and arterial pressure
5. Principles of cardio-vascular physiopathology
6. Arterial hypertension
7. Coronary insufficiency
8. Cardiac failure
II. Respiratory system
1. Introduction to respiratory system
2. Ventilation
3. Diffusion
4. Circulation
5. Blood gazes
6. Control of pH
7. Gaz exchanges
8. Respiratory mechanics
9. Control of ventilation
10. Unusual conditions (altitude...).
III. Digestive system
1. Introduction
2. Regulation processes
3. Energy and metabolism
4. Regulation of intakes
5. Mouth
6. Oesophagus
7. Stomach
8. Hormons of digestive tract
9. Pancreas
10. Intestine absorption
11. Liver
12. Colon
IV. Nephro-urinary system
1. Introduction
2. Glomerular filtration
3. Tubular function
4. Water and ions regulation
5. Kidney pathophysiology
6. Urinary tract
V. Endocrine system and metabolism
The course concerns human biochemistry and physiology, partim endocrine system and metabolism. In particular, it encompasses the following chapters:
1. Introduction
2. Mechanisms of action of hormones
3. The hormones of the energetic metabolism
Energetic metabolism
Insulin and diabetes
Glucagon
Epinephrine
Glucocorticoids
Thyroid hormones
4. Gastro-intestinal hormones
5. Water, electrolytes, and mineral elements
6. Growth
7. Reproduction
8. Cytokines
9. Mediators
VI Nervous system
Système sensoriels somatiques : somesthésie, vision, audition, gustation, olfaction
Système moteur somatique : unité motrice, contrôle segmentaire des unités motrices, contrôle supra-segmentaire, apprentissage
Cognition, émotion, comportement
Eveil et conscience
Homéostasie
Nervous system
6 ntroductory lessons:
- Overview on nervous system physiology
- Somatic sensory systems (somesthesia, vision,...)
- Somatic motor system
- Vegetative motor system
- Cognitive systems & state systems
- Homeostasis
The objective of this first part of the module is to introduce students with the fundamentals of physiology/biochemistry of the nervous system and special sense organs.
4 lessons on the pathophysiology and therapeutic stratégies of
- Nociception (pain)
- Disorders of the somatic motor systems
- Disorders of higher functions & emotions
- Disorders of homeostasis
Nervous system - specific concepts
1 lesson on the physiological bases of the study of human brain function using functional brain imaging
Learning outcomes of the learning unit
The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
Cardiovascular system
The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
More specifically, the learning objectives correspond to the table of contents of the course, described in detail in the "contents of the teaching unit" section.
Respiratory system
The objective of the course is to master the principles of biochemistry and physiology of the human cardio-vascular system. Furthermore, the student will have understood the importance of feedbacks and interactions between the different parts of the regulatory systems.
Nervous system
At the end of this course, the student will be able to describe the principles of operation
-general of the nervous system: communication by electrical and chemical signals
-somatic sensory systems (somesthesia, viaion, hearing, olfaction, taste, proprioception)
-the somatic motor system (automatic and voluntary control of muscle strength)
-the vegetative motor system (sympathic and parasympathic)
-the main cognitive functions and state systems (sleep, emotion, consciousness)
-homeostasis control
He will also be able to describe the physiopathological bases of the treatment
- pain
- physical motor disorders
-the main mental disorders
-homeostasis disorders
Nervous system - specific concepts
At the end of this course, the student will be able to describe how brain function can be studied in vivo using brain imaging techniques
Prerequisite knowledge and skills
General Biochemestry; General Physiology
Cardiovascular system
General Biochemestry; General Physiology
Respiratory system
General Biochemestry; General Physiology
Nervous system
General Biochemestry; General Physiology
Nervous system - specific concepts
Nervous system physiology & biochemistry
Planned learning activities and teaching methods
Lectures with active participation of students
Cardiovascular system
Lectures with active participation of students. All classes are podcast.
Respiratory system
Lectures with active participation of students
Nervous system
N/A
Nervous system - specific concepts
N/A
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face delivery
Cardiovascular system
Face-to-face delivery
Respiratory system
Face-to-face delivery or on-line lessons.
Nervous system
Face-to-face delivery
However, these teaching conditions will be adapted according to the requirements of the sanitary situation (COVID-19) and partially or completely moved online into virtual classrooms.
Nervous system - specific concepts
Face-to-face delivery
However, these teaching conditions will be adapted according to the requirements of the sanitary situation (COVID-19) and partially or completely moved online into virtual classrooms.
Recommended or required readings
Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition.
D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed
Cardiovascular system
Course syllabus, available on MyULg/eCampus
Respiratory system
Course syllabus, available on MyULg/eCampus
For neurophysiology here is a useful reference book:
Neurosciences, 5th edition.
D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. de boeck Ed
Nervous system
Course syllabus, available on MyULg/eCampus
Many learning objectives can also be reached by referring the following optional textbooks:
Mayo Clinic Medical Neurosciences: Organized by Neurologic Systems and Levels, (6 edn) 2017 Eduardo E. Benarroch, Jeremy K. Cutsforth-Gregory, Kelly D. Flemming. Edition Oxford academic
Neurosciences, 6ème édition, 2019 (traduite en français). D. Purves, G.J. Augustine, D. Fitzpatrick, W.C. Hall, A.-S LaMantia, J.O. McNamara, L.E. White. Editions de boeck.
Nervous system - specific concepts
Course syllabus, available on MyULg/eCampus
Assessment methods and criteria
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire )
Additional information:
End semester evaluations
Examinations are written. They include the following types of questions:
MCQs with certainty coefficients (see note on this subject on the eCampus).
Examinations will take place as on-line (if needed) or presential activities.
There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.
However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.
Cardiovascular system
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire )
Additional information:
End semester evaluations
Written evaluations will take place in june and in august/september. Evaluations will be organized the same day for all parts of the course Normal and Pathological Human Biochemistry and Physiology (NPHBP).
For the cardio-vascular module, the exam consists of Multiple Choice Questions (MCQ).
Respiratory system
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire )
Additional information:
End semester evaluations
The exams are written. They include the following types of questions:
MCQs with certainty coefficients (see note on this subject on the eCampus).
Examinations will take place as on-line (if needed) or presential activities.
There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.
However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.
Nervous system
Exam(s) in session
Any session
- In-person
written exam ( multiple-choice questionnaire )
Additional information:
The exams are written. They include the following types of questions:
MCQs with certainty coefficients (see note on this subject on the eCampus).
Examinations will take place as on-line (if needed) or presential activities.
There is no partial exemption for this course, either between the 1st and 2nd session or from one year to the next for the PHARMA, SBIM and DENTIST sections.
However, this rule does not apply to Master of Science in Nursing students. Partial exemptions may be granted.
Nervous system - specific concepts
same as BIOC1004-D
Work placement(s)
No training
Cardiovascular system
No training
Respiratory system
No training
Nervous system
No training
Nervous system - specific concepts
No training
Organizational remarks
No remark
Cardiovascular system
No remark
Respiratory system
No remark
Nervous system
No remark
Nervous system - specific concepts
No remark
Contacts
Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be
Cardiovascular system
Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
Respiratory system
Prof Didier CATALDO
didier.cataldo@uliege.be
Tel : 04 366 2521
Mme Jessica THYS (administrative assistent)
Jessica.thys@uliege.be
Pr Philippe Kolh
Philippe.kolh@uliege.be
04/3665196
04/3668445 (secretary)
Prof Gaetan GARRAUX
Tél : 04 3665950
ggarraux@uliege.be
Nervous system
Prof Gaetan GARRAUX ggarraux@uliege.be Tel (Mrs BOURDOUX, secretary): 04/3665950
Nervous system - specific concepts
Prof Gaetan GARRAUX ggarraux@uliege.be Tel (Mrs BOURDOUX, secretary): 04/3665950