Duration
15h Th, 5h Mon. WS
Number of credits
| Master in bio-informatics and modelling (120 ECTS) | 2 crédits | |||
| Master in biochemistry and molecular and cell biology (120 ECTS) | 2 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
Advanced methods in mass spectrometry.
Electrospray ionisation and fragmentation of biomolecules.
Native mass spectrometry - Analysis of macromolecular assemblies.
Hydrogen-deuterium exchanges coupled to mass spectrometry.
Chemical Cross-Linking monitored by mass spectrometry.
Basis of ion mobility.
Imaging by mass spectrometry: Principles and applications.
Learning outcomes of the learning unit
This course aims to present to the student the main mass spectrometry-based approaches useful in biology, biochemistry or again microbiology thematic.
The theory of each part will be illustrated by recent examples extracted from the literature.
Prerequisite knowledge and skills
Molecular structures, mainly peptides et proteins.
Notions of mass spectrometry.
Planned learning activities and teaching methods
Theory.
Exercises illustrating the course.
Visit of the laboratory and discovery of the main instruments.
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Recommended or required readings
The exam will be divided into three parts:
1- True/False testing: to check the good understanding of the whole teaching.
2- Open questions: to allow a more global expression of the students on the dispensed learning.
3- Case study from the literature.
Work placement(s)
Organisational remarks and main changes to the course
Contacts
Prof. Loïc Quinton Laboratory of Mass Spectrometry - MolSys Research Unit Bat B6C, Local 0/R66 Tel: +0032 4 366 3679 Email: loic.quinton@uliege.be