Duration
40h Th, 20h Pr
Number of credits
| Bachelor in biology | 5 crédits |
Lecturer
Language(s) of instruction
French language
Organisation and examination
Teaching in the second semester
Schedule
Units courses prerequisite and corequisite
Prerequisite or corequisite units are presented within each program
Learning unit contents
- Thermodynamic
Free energy and activation energy
Free energy and oxydoreduction potential
Reversibility of the biochemical reaction
chemical potential
Osmose phenomenon
Introduction to the mechanism of diffusion
- Nature of the non covalent interactions between biomolecules
-Organisation levels of proteins
- Enzymes
Co-enzymes, co-factors and co-substrates
Introduction to enzymatic kinetic
Introduction to allosteric mechanism
Example of catalysis: chymotrypsin and the family of active site serine proteolytic enzymes
- Proteins of interest
Myoglobin and hemoglobin
Immunoglobulins
- Carbohydrates and glycoproteins
- Lipids and lipoproteins
-Introduction to bioenergetics
-Carbohydrate catabolism
Glycogenolysis
Glycolysis and its regulation
Destiny of pyruvate in anaerobic conditions
Destiny of pyruvate in aerobic condition
Oxydative phosphorylation
- Gluconeogenesis and its regulation
destiny of carbohydrates in the organism
-Degradation of fatty acids and lipids
-Protein degradation and destiny of amino acids
- Biochimistry of the gene - DNA
DNA composition
Structure of DNA
Gentic information and DNA
DNA organisation in chromosomes
- Dynamic of genes
DNA replication in prokaryotes
DNA replication in eukaryotes
Genetic code
Transcription and messager RNA
- Protein biosynthesis
Transfer RNA or tRNA
Ribosomes
mechanism of protein synthesis
Destiny of proteins
-Control of gentic expression
Learning outcomes of the learning unit
The lectures will be devoted on :
- physical and chemical basis of biochemistry
- molecular basis of metabolic pathways involved in the regulation of biological process
Prerequisite knowledge and skills
Basic lecture in inorganic and organic chemistry
Courses of general biology
Planned learning activities and teaching methods
3 lectures
- kinetic
- Determination od protein concentration
- Dyalisis and molecular sieve
Place: Batiment de chimie (B6 - sart Tilman) pour des travaux pratiques de candidature
Mode of delivery (face to face, distance learning, hybrid learning)
Face-to-face course
Additional information:
20 lecture of 2 hours
3 laboratory sessions
1 exercice session
Recommended or required readings
Overheads and Power Point presentation
Syllabus
Exam(s) in session
May-June exam session
- In-person
written exam ( open-ended questions ) AND oral exam
August-September exam session
- In-person
written exam ( open-ended questions ) AND oral exam
Additional information:
Written and oral examination
Work placement(s)
Organisational remarks and main changes to the course
f the overall mark for the General Biochemistry exams is less than 10/20, students will sit the exam in the September session. Partial exemptions may be granted if the oral or written examination was passed in the June session. However, with the exception of practical work, exemptions from the oral or written examination are not carried over to the following academic year.
Contacts
Lectures:
Galleni Moreno, Local 3/7, Institut de Chimie , B6. Sart Tilman
Phone:04/3663549 - Fax:04/3663364 - Email:mgalleni@ulg.ac.be
Practical lectures:
Mercuri Paola, Chargé de Recherche
local 2/10, institut de Chimie, B6a. Sart Tilman
Phone: 04/3669220- Fax: 04/3663396 - Email:pmercuri@uliege.be